genomic change – Communicable Diseases Research

Temporal dynamics of SARS-CoV-2 genome and detection of variants of concern in wastewater influent from two metropolitan areas in Arkansas

Article

Published on 2022-11-252022-11-15
Journal: The Science of the total environment
[Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제,

Genome sequence diversity of SARS-CoV-2 obtained from clinical samples in Uzbekistan

우즈베키스탄의 임상 샘플에서 얻은 SARS-CoV-2의 게놈 서열 다양성

Article

Published on 2022-06-272022-09-11
Journal: PLoS ONE
[Category] COVID19(2023년), SARS, 변종,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected Alpha Amino acid amino acid substitution annotation association change clade clades clinical isolates clinical sample Cluster coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity D614G Deleterious Deletion Delta Denmark disease severity evidenced Evolution female followed by genetic diversity Genome Genomic analysis genomic change Genotype help Identified isolate isolates male Missense Missense mutation Missense mutations Mutation Nextstrain NSP Nsp12 nsp13 Nsp3 nsp4 NSP6 nucleotide Open reading frame ORF ORF7a Pathogenesis PCR-positive patient Protein reading regions Research Russia SARS-CoV SARS-CoV-2 SARS-CoV-2 strain SARS-CoV-2 variant SARS-CoV-2 variants sequence severe acute respiratory syndrome Coronavirus severity significantly SNP SNPs subclade Substitution synonymous Tashkent the Spike two group two groups USA variant variants Variation WGS whole genome sequence with COVID-19
[DOI] 10.1371/journal.pone.0270314 PMC 바로가기 [Article Type] Article

Integration of whole genome sequencing and transcriptomics reveals a complex picture of the reestablishment of insecticide resistance in the major malaria vector Anopheles coluzzii

전체 게놈 시퀀싱 및 전 사체의 통합은 주요 말라리아 벡터 Anopheles coluzzii에서 살충제 저항성의 재건에 대한 복잡한 그림을 보여줍니다.

Research Article

Published on 2021-12-232022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] alteration Anophele approach block change changes in colony complex complexity determine diagnostic Diagnostic markers elevated expression of gene Genetic genetic background Genome genomic genomic change increase in increased respiratory rate increasingly insecticide integration inversion Laboratory malaria malaria control malaria vector marker mechanism metabolism microbial Microbiome original oxidative phosphorylation pathway phenotype Population Pyrethroids respiratory rate reveal RNAseq Sequencing subject subset susceptible Transcriptome transcriptomic transcriptomics translated whole genome Whole genome sequencing
[DOI] 10.1371/journal.pgen.1009970 PMC 바로가기 [Article Type] Research Article

Molecular characterization of SARS-CoV-2 from Bangladesh: implications in genetic diversity, possible origin of the virus, and functional significance of the mutations

Research Article

Published on 2021-08-212022-10-31
Journal: Heliyon
[Category] COVID-19,

[키워드] accompanied Analysis ancestor B-cell Bangladesh China Chittagong circulating clade Clinical data Complete country COVID-19 COVID-19 pandemic CpG D614G Deletion Diagnosis downloaded Epidemiology epitope European country evade event Evolution functional genetic diversity Genome genome sequence Genome sequencing genomic change GISAID GISAID database Host immune response implication include India insertions isolate isolates less Missense Missense mutation MOST Mutation mutations Nextstrain nucleotide occurred ORF7a ORF8 gene P323L Pathogenesis PCR Phylogeny predict predicted prevalent RdRP reduce reference sequence Region reported reveal RT-PCR SARS-CoV-2 SARS-CoV-2 genome selective sequence severity single nucleotide variations Spike protein submitted synonymous T-cell target region the disease the SARS-CoV-2 virus unique variant viral clearance viral replication virus Wuhan
[DOI] 10.1016/j.heliyon.2021.e07866 PMC 바로가기 [Article Type] Research Article

Post-vaccination COVID-19: A case-control study and genomic analysis of 119 breakthrough infections in partially vaccinated individuals

백신 접종 후 COVID-19: 부분 백신 접종을 받은 개인의 119개 돌발성 감염에 대한 사례 대조 연구 및 게놈 분석

Major Article

Published on 2021-08-192022-09-10
Journal: Clinical Infectious Diseases: An Official Publicat
[Category] SARS, 변종, 유전자 메커니즘, 치료기술,

[키워드] 95%CI Admission age and sex all-cause mortality allele Analysis B.1.1.7 B.1.525 BNT162b2 BNT162b2 mRNA Breakthrough infection case-control study ChAdOx1 ChAdOx1 nCoV-19 Control COVID-19 COVID-19 pandemic Ct values died difference dose E484K escape mutation evaluated first vaccination Genome sequencing Genomic analysis genomic change Genomics hospital Hospital admission Hospital admissions Infection IQR Lineage median Mortality Mutation NNT nucleotide Patient patients with COVID-19 Phylogenetic polymorphism predominant reduce reduction in mortality Relative risk Result risk RR reduction SARS-COV-2 infection single nucleotide Single nucleotide polymorphism SNP subgroup subgroup analysis treat vaccinated individual vaccination Vaccine variant was performed with infection
[DOI] 10.1093/cid/ciab714 PMC 바로가기 [Article Type] Major Article

Zoonotic and Reverse Zoonotic Transmissibility of SARS-CoV-2

Review

Published on 2021-06-092022-10-04
Journal: Virus research
[Category] MERS, SARS, 조류인플루엔자, 치료기술,

Global cataloguing of variations in untranslated regions of viral genome and prediction of key host RNA binding protein-microRNA interactions modulating genome stability in SARS-CoV-2

바이러스 게놈의 번역되지 않은 영역의 변이에 대한 글로벌 카탈로그 및 SARS-CoV-2에서 게놈 안정성을 조절하는 주요 숙주 RNA 결합 단백질-마이크로RNA 상호작용 예측

Research Article

Published on 2020-08-112022-08-13
Journal: PLoS ONE
[Category] Biochemistry, COVID-19, MERS, SARS,

[키워드] 3’-UTR aligned Anti-viral binding binding site caused changes in checked Clustal Omega coding region Complete Compound Consequences coronavirus COVID-19 pandemic Critical cross-talk cut-off downloaded effort explain FASTA format Genome genomic change geographical regions GISAID global change Host Human coronavirus human host idea identify Infection Influenza initiative Interaction investigated knowledge lung mechanism microRNA MicroRNAs miRNAs modulating phenomenon Region regions Regulation Result RNA RNA binding protein SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genome sequence SARS-COV-2 infection selected sequence information stability tissue unique untranslated regions UTR variant variants Variation variations Viral viral genome viral RNA genome virus
[DOI] 10.1371/journal.pone.0237559 PMC 바로가기 [Article Type] Research Article

An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons

말라리아 매개체 Anopheles funestus의 살충제 저항성의 아프리카 전역 게놈 진화에는 선택적 스윕, 복제 수 변이, 유전자 전환 및 트랜스포존이 포함됩니다

Research Article

Published on 2020-06-042022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] alleles analysis Analysis Anophele approach bed net complex copy number cytochrome P450 driven by Effectiveness Evidence evidence of Evolution exhibited gene conversion gene flow Genes genetic diversity genomic genomic change genomic region glutathione greater haplotypes highlighting independent insecticide insecticides insertion Intervention Local loci locus malaria malaria control malaria vector management metabolic Metabolic resistance molecular molecular evolution Multiple performed Population pyrethroid respond risk selection pressure selective sweep selective sweeps signature Spread Temporal transposon Variation variations vector control whole genome
[DOI] 10.1371/journal.pgen.1008822 PMC 바로가기 [Article Type] Research Article

Comparative Genomics of the Sigatoka Disease Complex on Banana Suggests a Link between Parallel Evolutionary Changes in Pseudocercospora fijiensis and Pseudocercospora eumusae and Increased Virulence on the Banana Host

바나나에 대한 Sigatoka 질병 복합체의 비교 유전체학은 Pseudocercospora fijiensis와 Pseudocercospora eumusae의 병렬 진화적 변화와 바나나 숙주의 독성 증가 사이의 연관성을 시사합니다

Research Article

Published on 2016-08-112022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] acquisition adaptation analysis analyzed assimilation banana biological process caused cell walls change changes in Comparative Comparative analysis Comparative genomics complementary complex conserved convergent evolution core gene Degradation disease disease control Diversity Dothideomycetes driven by effective effector proteins effectors Evolution evolutionary relationships facilitate facilitated fungi gene count gene families gene family Genes Genome genome architecture genome sequence genomes genomic genomic change Genomics higher efficiency Host host immune system identify increase in Increased indicated involved LTR management metabolic pathway metabolic pathways metabolism Modification pathogen pathogenic Pathogens plant cell profile proliferation Radiation remained sequenced Seven significant difference significant differences speciation Still supported understanding utilization virulence virulent
[DOI] 10.1371/journal.pgen.1005904 PMC 바로가기 [Article Type] Research Article

Genomic change in hepatitis B virus associated with development of hepatocellular carcinoma

Article

Published on 2016-06-212023-06-19
Journal: World journal of gastroenterology
[Category] B형 간염,

[키워드] Chronic Hepatitis B genomic change genotype C Hepatitis B virus hepatocellular carcinoma.
[DOI] 10.3748/wjg.v22.i23.5393 PMC 바로가기